ROLE OF OCCUPATIONAL THERAPY IN SARS-CoV/ SARS -CoV-2


   ROLE OF OCCUPATIONAL THERAPY
IN SARS-CoV/ SARS -CoV-2
                                       
            
  1. INTRODUCTION:
·         Severe acute respiratory syndrome (SARS) is a communicable viral disease, caused by a new strain of corona virus, which differs considerably in genetic structure from previously recognized corona virus. The most common symptoms in patient progressing to SARS include fever, malaise, chills, headache myalgia, dizziness, cough, sore throat and running nose. In some cases there is rapid deterioration with low oxygen saturation and acute respiratory distress requiring ventilator support. It is capable of causing death. In as many as 10 per cent cases (1).
  1. PROBLEM STATEMENT:
·         The earliest case was traced to a health care worker in China, in late 2002, with rapid spread to Hong Kong, Singapore, Vietnam, Taiwan and Taranto. As of early August 2003, about 8,422 cases were reported to the WHO from 30 countries with 916 fatalities (2)
  1.  EPIDEMIOLOGICAL:                         
·         Health care workers, especially those involved in procedures generating aerosols, accounted for 21 per cent of all cases. Maximum virus excretion from the respiratory tract occurs on about day 10 of illness and then declines. The efficiency of transmission appears to be greatest following exposure to severely ill patients or those experiencing rapid clinical deterioration, usually during the second week of illness. When symptomatic cases were isolated within 5 days of the onset of illness, few cases of secondary transmission occurred. There was no evidence that patient transmits infection 10 days after fever has resolved. Children are rarely affected by SARS. To date, there have been two reported cases of transmission from children to adults and no report of transmission from child to child. Three separate epidemiological investigations have not found any evidence of SARS transmission in schools. Furthermore, no evidence of SARS has been found in infants of mothers who were infected during pregnancy. International flights have been associated with the transmission of SARS from symptomatic probable cases to passengers or crew. WHO recommends exit screening and other measures to reduce opportunities for further international spread associated with air travel during the epidemic period.
  1. INCUBATION PERIOD:
·         The incubation period has been estimated to be 2 to 7 days, commonly 3 to 5 days (1)
  1.  MODE OF TRANSMISSION:
·         The primary mode of transmission appears to be through direct or indirect contact of mucous membranes of eyes, nose, or mouth with respiratory droplets or fomites. The use of aerosol-generating procedures (end tracheal intubation, bronchoscope, and mobilization treatments) in hospitals may amplify the transmission of the SARS corona virus. The virus is shed in stools but the role of faecal-oral transmission is unknown. The natural reservoir appears to be the horseshoe bat (which eats and drops fruits ingested by civets, the earlier presumed reservoir and a likely amplifying host). The SARS virus can survive for hours on common surfaces outside the human body, and up to four days in human waste. The virus can survive at least for 24 hours on a plastic surface at room temperature, and can live for extended periods in the cold.
  1.  CASE STUDY (4) 
·        The case definition is based on current understanding of the clinical features of SARS, and available epidemiological data. It may be revised as new information accumulates. Case definition for notification of SARS under the international health regulation (2005) In the period following an outbreak of SARS, a notifiable case of SARS is defined as an individual with laboratory confirmation of infection with SARS corona virus (SARS-CoV) who either fulfils the clinical case definition of SARS or has worked in a laboratory handling live SARS-CoV or storing clinical specimens infected with SARS-CoV.
Clinical case definition of SARS:
·         A history of fever, or documented fever
·         One or more symptoms of lower respiratory tract illness (cough, difficulty in breathing, shortness of breath)  
·         Radiographic evidence of lung infiltrates consistent with pneumonia or acute respiratory distress syndrome (ARDS) or autopsy findings consistent with the pathology of pneumonia or ARDS without an identifiable cause No alternative diagnosis fully explaining the illness.
Diagnostic tests required for laboratory confirmation of SARS:
·         Conventional reverse transcriptase PCR {RT-PCR) and real-time reverse transcriptase PCR (real-time RT-PCR). Assay detecting viral RNA present in:
·         At least 2 different clinical specimens (e.g. nasopharyngeal and stool specimens) OR The same clinical specimen collected on 2 or more occasions during the course of the illness (e.g. sequential nasopharyngeal aspirates)
OR
·         A new extract from the original clinical sample tested positive by 2 different assays or repeat RT-PCR or real-time RT-PCR on each occasion of testing OR  Virus culture from any clinical specimen.
     2.  Enzyme-linked immunosorbent assay (ELISA) and immunofluorescent assay (IFA)
·         Negative antibody test on serum collected during the acute phase of illness, followed by positive antibody test on convalescent-phase serum, tested simultaneously OR
·         A 4-fold or greater rise in antibody titre against SARS-CoV between an acute-phase serum specimen and a convalescent-phase serum specimen (paired sera), tested simultaneously.
·         In the absence of known SARS-CoV transmission to humans, the positive predictive value of a SARS-CoV diagnostic test is extremely low; therefore, the diagnosis should be independently verified in one or more WHO international SARS reference and verification network laboratories. Every single case of SARS must be reported to WHO.
STUDY:2
·         Corona viruses are a large family of viruses that are known to cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS).
·         A novel corona virus (COVID-19) was identified in 2019 in Wuhan, China. This is a new corona virus that has not been previously identified in humans. This course provides a general introduction to COVID-19 and emerging respiratory viruses and is intended for public health professionals, incident managers and personnel working for the United Nations, international organizations and NGOs.As the official disease name was established after material creation, any mention of nCoV refers to COVID-19, the infectious disease caused by the most recently discovered corona virus.(6)
·         The 2019 novel corona virus (SARS-CoV-2) outbreak and spread of the associated disease (COVID-19) is a rapidly evolving situation. To manage the threat of continued SARS-CoV-2 infection and the risk to public health caused by COVID-19, health professionals need up-to-date information and guidance on global surveillance, infection control measures and identifying and caring for people with COVID-19. This resource area brings together information about the outbreak and COVID-19 content from ERS and ELF
What is the novel corona virus:
·         Corona viruses are a large family of viruses that can cause illness ranging from the common cold to more severe diseases like Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS).
·         The 2019 novel corona virus, called 'SARS-CoV-2' (previously referred to as 2019-nCoV), is a new strain that has not been identified in humans before. The disease that is caused by SARS-CoV-2 is called 'COVID-19'.
OUTBREAK SUMMARY:
·         On 31 December 2019, the World Health Organization (WHO) was informed of several cases of viral pneumonia of unknown cause detected in Wuhan City, China. The outbreak has rapidly evolved, affecting other parts of China and many countries worldwide in Asia, Europe, North and South America, Australia and Africa. On 11 March 2020, WHO labelled the COVID-19 outbreak as a pandemic.ERS recommends consulting the WHO's daily situation reports for the latest updates on the number of people who are being treated for COVID-19 and the geographic spread of SARS-CoV-2
Clinical features:
·         The WHO reports that human-to-human transmission is occurring with a preliminary R0 estimate of 1.4–2.5. Current estimates of the incubation period of the virus range from 2–14 days, and the virus seems to be transmitted mainly via flu-like symptoms and respiratory droplets that people sneeze, cough, or exhale.
·         Typical symptoms of COVID-19 include fever, cough, difficulty breathing, muscle pain and tiredness. More serious cases develop severe pneumonia, acute respiratory distress syndrome, sepsis and septic shock.
·         Generally, older people and those with underlying conditions (such as hypertension, heart disorders, diabetes, liver disorders, and respiratory disease) are expected to be more at risk of developing severe symptoms.
·         The evidence from analyses of cases to date is that COVID-19 infection causes mild disease (i.e. non-pneumonia or mild pneumonia) in about 80% of cases and most cases recover; 14% have more severe disease and 6% experience critical illness.(7)
  1.  INVESTIGATION:

·         Chest X-ray findings typically begin with a small, unilateral patchy shadowing, and progress over 1-2 days to become bilateral and generalized, with interstitial/confluent infiltration. Adult respiratory distress syndrome has been observed in a number of patients in the end stages.
  1.  COMPLICATIONS:                  
·         As with any viral pneumonia, pulmonary decomposition is the most feared problem. ARDS occurs in about 16% patients, and about 20-30% of patients require intubation and mechanical ventilation. Sequelae of intensive care include infection with nosocomial pathogens, tension pneumothorax from. ventilation at high peak pressures, and non-cardiogenic pulmonary edema.
  1.  PROGNOSIS:
·         The overall mortality rate of identified cases is about 14%. Mortality is age-related, ranging from less than 1 % in persons under 24 years of age to greater than 50% in persons over 65 years of age. Poor prognostic factors include advanced age, chronic hepatitis B infection treated with lamivudine, high initial or high peak lactate dehydrogenase concentration, high neutrophil count on presentation, diabetes mellitus, acute kidney disease, and low counts of CD4 and CD8 on presentation. Many subclinical cases probably go undiagnosed. Seasonality, as with influenza, is not established (5).
  1. TREATMENT:INTERDISCIPLINARY APPROACH   
·         Rehabilitation has been defined as "the combined and coordinated use of medical, social, educational and vocational measures for training and retraining the individual to the highest possible level of functional ability" interdisciplinary team approach  the involves disciplines such as physical  medicine, occupational therapy,  physiotherapy, social work, vocational guidance and placement services. The following areas of concern in rehabilitation have been identified:
1.       Medical rehabilitation - restoration of function.
2.      Vocational rehabilitation - restoration of the capacity to earn a livelihood.
3.      Social rehabilitation - restoration of family and social relationships.
4.      Psychological rehabilitation restoration of personal dignity and confidence (15,16)

·         As there is no vaccine against SARS, the preventive measures for SARS control are appropriate detection and protective measures which include:
1.        Prompt identification of persons with SARS, their movements and contacts
2.        Effective isolation of SARS patients in hospitals 3. Appropriate protection of medical staff treating these patients
3.      Comprehensive identification and isolation of suspected SARS cases
4.       Simple hygienic measures such as hand-washing after touching patients, use of appropriate and well-fitted masks, and introduction of infection control measures
5.       Exit screening of international travellers
6.      Timely and accurate reporting and sharing of information with other authorities and/or governments.

10.1. OCCUPATIONAL THERAPY: domains are included in the Practice Framework
1.       Performance Areas
2.      Performance Skills
3.      Performance Patterns
4.      Context
5.      Activity demands
6.      Client Factors(14)


PREVENTION:


1. PRIMORDIAL:

1.      Phase:  Underlying economic, social, and environmental conditions leading to causation
2.      Aim: Establish and maintain conditions that minimize hazards to health
3.      Occupational therapy role:
Ø  Preventive education
v  Health  communication 
1.      Mass approach  ( TV, Radio, news paper, printed material, direct   mailing, Internet)
2.       Group approach : (lecture ,demonstrating)
3.       Individual: (home visit, personal letter )

2. PRIMARY PREVENTION:
1.      Phase: specific causal factors
2.      Aim: reduce the incidence
3.      Occupational therapy role:
Ø  Self management skills education
Ø  Home management skiills education
Ø  Environmental adaptation


3. SECONDARY PREVENTION:

1.      Phase: Early stage of disease
2.      Aim: Reduced the prevalence
3.      Occupational therapy role: (Based on severity of the illness)
Ø  Patient and family Education (regarding disease process and recovery)
Ø  Preventive techniques: Adjunctive methods  (bed sore, bed position, feeding techniques, patient handling method, dyspnoea control posture, etc....)
Ø  Graded respiratory exercises program
Ø  Increase knowledge of approximate metabolic cost of activities METs
Ø  Maintained or improve ROM, strength, and Cardio pulmonary endurance
Ø  Self management education
Ø  Psychological adaptation
Ø  Energy conservation techniques
Ø  Work simplification techniques
Ø  Joint protection techniques
Ø  Self help skills adaptation and modification
Ø  Environmental adaptation and modification
Ø  Home adaptation and modification

 4. TERTIARY PREVENTION:
1.      Phase: Late state of diseases
2.      Aim: Reduce the number and impact of complication
3.      Occupational therapy role:(Based on severity of illness)
Ø  Psychological adaptation
Ø  Environmental adaptation and modification
Ø  Home adaptation and modification
Ø  Preventive techniques. Patient and family Education (regarding disease process and recovery)
Ø  Preventive techniques: adjunctive methods (sore, bed position, feeding techniques, patient handling method, dyspnoea control posture, etc....)
Ø  Graded respiratory exercises program
Ø  Increase knowledge of approximate metabolic cost of activities METs
Ø  Maintained or improve ROM, strength, and Cardiopulmonary endurance
Ø  Self management education
Ø  Energy conservation techniques
Ø  Work simplification techniques
Ø  Joint protection techniques
Ø  Self help skills adaptation and modification(8,9,10,11,12,13)

DETAILED ABOUT ROLE OF OCCUPATIONAL THERAPY IN SARS-Co V/ SARS -CoV-2:
1.  Preventive technique: adjunctive method
These positions are helpful when you have shortness of breath during activity, emotional excitement, the prevention of primary complication and exposure to adverse weather condition.
POSITIONING:
Sitting
1.      Rest your feet flat on the floor.
2.      Lean your chest forward slightly.
3.      Rest your elbows on your knees or rest your chin on your hands.
4.      Relax your neck and shoulder muscles.
-OR-
5.      Rest your feet flat on the floor.
6.      Lean your chest forward slightly.
7.      Rest your arms on a table.
8.      Rest your head on your forearms or on some pillows

Standing
1.      Stand with your feet shoulder width apart.
2.      Lean your hips against a wall.
3.      Rest your hands on your thighs.
4.      Relax your shoulders, leaning forward slightly and dangling your arms in front of you.
-OR-
1.      Rest your elbows or hands on a piece on furniture, just below shoulder height.
2.      Relax your neck, resting your head on your forearms.
3.      Relax your shoulders.

Sleeping
1.      Lie on your side with a pillow between your legs and your head elevated with pillows. Keep your back straight.
-OR-
1.      Lie on your back with your head elevated and your knees bent, with a pillow under your knees.(18)
Prone
1.      Close eyes and protect with gel or pad.
2.      Place the patient's palms against their thighs, thumbs upwards, elbows straight and shoulders neutral.
3.      Slide the patient to the edge using a Sliding sheet.
4.      Roll patient into the lateral position using the underneath sheet.
5.      Roll patient into prone.
6.      'Swimmers position' - elbow in which the head is semi-rotated should be flexed to no more than 90° to avoid ulnar nerve stretch, and the other arm internally rotated by the side.
7.      Ensure that women's breasts or men's genitals are not compressed.
8.      Place two pillows under each shin to prevent peroneal nerve stretch, positioning them to avoid knee and toe pressure from mattress. (17)

2. GRADED BREATHING EXERCISE PROGRAM
BREATHING ACTIVITY:
Pursed lip breathing
1.      Its been shown to reduce how hard a person has to work to breathe.
2.      It helps release air trapped in the lungs.
3.      It promotes relaxation.
4.      It reduces shortness of breath.
5.      Practicing this technique 4 to 5 times daily can help.
6.      While keeping your mouth closed, take a deep breath in through your nose, counting to 2. Follow this pattern by repeating in your head “inhale, 1, 2.” The breath does not have to be deep. A typical inhale wills do. Put your lips together as if you are starting to whistle or blow out candles pursed, slowly breathe out by counting to 4. Don’t try to force the air out, but instead breathe out slowly through your mouth.
DIAPHRAGMATIC BREATHING
 Diaphragmatic or abdominal breathing helps to retrain this muscle to work more effectively.
1.      While sitting or lying down with your shoulders relaxed, put a hand on your chest and place the other hand on your stomach.
2.      Take a breath in through your nose for 2 seconds, feeling your stomach move outward. You’re doing the activity correctly if your stomach moves more than your chest.
3.      Purse your lips and breathe out slowly through your mouth, pressing lightly on your stomach. This will enhance your diaphragm’s ability to release air.
4.      Repeat the exercise as you are able to.
COORDINATED BREATHING
1.      Inhale through your nose before beginning an exercise.
2.      While pursing your lips, breathe out through your mouth during the most strenuous part of the exercise. An example could be when curling upward on a bicep curl.
DEEP BREATHING
Deep breathing prevents air from getting trapped in your lungs
1.      Sit or stand with your elbows slightly back. This allows your chest to expand more fully.
2.      Inhale deeply through your nose.
3.      Hold your breath as you count to 5.
4.      Release the air via a slow, deep exhale, through your nose, until you feel your inhaled air has been released.(19)

3. INCREASE KNOWLEDGE OF APPROXIMATE METABOLIC COST OF ACTIVITIES:

MET: 1.0 to 1.4
1.       ADL and mobility: sitting, self-feeding, wash hands and face, bed mobility transfers progressively  increase sitting tolerance
2.      Exercise:
§  Supine = A or AA exercise to all extremities (10-15x per extremity)
§  Sitting = A or AA exercise only neck and LEs include deep breathing exercises
3.        Recreation: reading, radio, table games (noncompetitive), light work

MET: 1.4 to 2.0
1.       ADL and mobility:
§  Sitting = self-bathing, shaving, grooming, dressing in hospital unlimited sitting
§  Ambulation = at slow pace, in room, as tolerated
2.       Exercise:
§  Sitting = A exercise to all extremities (increasing repetitions per MD) NO ISOMETRICS
     3. Recreation:
§  Sitting = crafts (painting, knitting, sewing, mosaics, embroidery) NO ISOMETRICS
MET: 2.0 to 3.0
1.        ADL and mobility:
§  Sitting = showing in warm water, homemaking tasks with brief standing periods to  transfer light items, ironing
2.      Exercise:
      • Sitting = wheelchair mobility, limited distances
      • Standing = A  Exercise to all extremities and trunk (increasing repetitions per MD)  May include balance exercises  Light mat activities without resistance  
      • Ambulation = begin progressive ambulation at 0% grade and comfortable pace
3.       Recreation:
§  Sitting = card playing, crafts, piano, machine sewing, typing (per MD

MET: 3.0 to 3.5
1.      ADL and mobility:
1.             
§  Standing = total washing, dressing, shaving, grooming, showering in warm water; kitchen/homemaking activities while practicing energy conservation (light vacuuming,  dusting, and sweeping, washing light clothes)
2.      Exercise:
2.              
                                                      ii.            Standing = continue all previous exercise, progressively increasing repetitions, speed of  repetitions may include additional exercises to increase workload up to 3.5 MET, balance, and mat activities with mild resistance
                                                    iii.            Ambulation = unlimited on level surfaces in and/or outside (per MD) progressively increasing speed  and/or duration for periods up to 15-20 minutes or until target heart rate is reached (per MD)
                                                    iv.            Stairs = may begin slow stair climbing to patient's tolerance up to 2 flights.                
                                                      v.            Treadmill = 1 mph at 1%  grade, progressing to 1.5 mph at 2% grade (per MD) cycling = up to 5.0 mph without
3.      Recreation: candlepin bowling, canoeing (slow rhythm, pace), golf putting, light gardening (weeding and planting), driving (per MD

MET: 3.5 to 4.0:
1.      ADL and mobility standing = washing dishes, washing clothes, ironing, hanging light clothes, and  making beds
2.      Recreation: swimming (slowly) light carpetry golfing (using power cart) light home repairs
3.      Exercise:
§  Standing = continue exercises in stage IV progressively increasing repetitions and speed of  repetitions may add additional exercises to increase workload up to 4.0 MET
§  Ambulation = as in stage IV, increasing speed up to 2.5 mph on level surfaces (per MD)         
§  Stairs = as in  stage IV and progressively increasing patient's tolerance
§  Treadmill = 1.5 mph at 2% grade,  progressing to 1.5 mph at 4% grade up to 2.5 mph at 0% grade (per MD
§  Cycling = up to 8 mph without resistance (per MD) May use up to 7 to 10 lb weight for upper and lower extremity exercises in sitting
MET: above  4.0
1.      ADL and mobility:
      • Standing = showering in hot water, hanging and/or wringing clothes, mopping, stripping and making beds, raking recreation: swimming (no advanced strokes) slow dancing ice  or roller skating (slowly) volleyball badminton table tennis (noncompetitive) light  calisthenics
      • Standing = continue exercises in stage IV progressively increasing repetitions and speed of repetitions  may add additional exercises to increase workload up to 4.0 MET
      • Ambulation = as in stage V, increasing speed to 3.5 mph on level surfaces (per MD)
      • Stairs = as in stage  IV and progressively increasing patient's tolerance
      • Treadmill = 1.5 mph at 5 to 6% grade progressing to 3.5 mph at 0% grade (per MD)
      • Cycling= up to 10 mph without resistance  May use up to 10 to 15lb weight in UE and LE exercises in sitting.(20)

4. EXERCISE OR ACTIVITIES MAINTAINED ROM, STRENGTH, AND CARDIOPULMONARY ENDURANCE:

 Passive ROM
     Indications for PROM
·         A patient is not able to or not supposed to actively move a segment or segments of the body, on complete bed rest, movement is provided by an external source.
    Goals for PROM
1.      Maintain joint and connective tissue mobility
2.       Minimize the effects of the formation of contractures
3.      Maintain mechanical elasticity of muscle
4.      Assist circulation and vascular dynamics
5.      Enhance synovial movement for cartilage nutrition and diffusion of materials in the joint
6.      Decrease or inhibit pain
7.      Assist with the healing process after injury or surgery
8.      Help maintain the patient’s awareness of movement Other Uses for PROM
9.      When a therapist is examining inert structures, PROM is used to determine limitations of motion, to determine joint stability, and to determine muscle and other soft tissue elasticity.
Active and Active-Assistive ROM
·         Patients gain control of their ROM, they are progressed to manual or mechanical resistance exercises to improve muscle performance for a return to functional activities .AROM can be used for aerobic conditioning programs
Goals for AROM
1.      Maintain physiological elasticity and contractility of the participating muscles
2.      Provide sensory feedback from the contracting muscles
3.      Provide a stimulus for bone and joint tissue integrity
4.      Increase circulation and prevent thrombus formation
5.      Develop coordination and motor skills for functional activities(21)
EXERCISE:
Warm-Up Period:
Physiological  Responses During this period there is:
1.      An increase in muscle temperature. The higher temperature increases the efficiency of muscular contraction by reducing muscle viscosity and increasing the rate of nerve conduction.
2.      An increased need for oxygen to meet the energy demands for the muscle. Extraction from hemoglobin is greater at higher muscle temperatures, facilitating the oxidative processes at work.
3.      Dilatation of the previously constricted capillaries with increases in the circulation, augmenting oxygen delivery to the active muscles and minimizing the oxygen deficit and the formation of lactic acid.
4.      Adaptation in sensitivity of the neural respiratory center to various exercise stimulants.An increase in venous return. This occurs as blood flow is shifted centrally from the periphery.
Purposes:
The warm-up also prevents or decreases:
1.      The susceptibility of the musculoskeletal system to injury.
2.      The occurrence of ischemic electrocardiographic (ECG)changes and arrhythmias.
Guidelines:
 The warm-up should be gradual and sufficient to increase muscle and core temperature without causing fatigue or reducing energy stores. Characteristics of the period include:
1.      A 10-minute period of total body movement exercises,such as calisthenics, and walking slowly.
2.      Attaining a heart rate that is within 20 beats/min of the target heart rate.
Aerobic Exercise Period:
·         The aerobic exercise period is the conditioning part of the exercise program. Attention to the determinants of intensity, frequency, duration, and mode of the program, as previously discussed, has an impact on the effectiveness of thevprogram. The main consideration when choosing a specific method of training is that the intensity be great enough to stimulate an increase in stroke volume and cardiac output and to enhance local circulation and aerobic metabolism in the appropriate muscle groups. The exercise period must be within the person’s tolerance, above the threshold level for adaptation to occur, and below the level of exercise that evokes clinical symptoms.
1.      In aerobic exercise, submaximum, rhythmic, repetitive,dynamic exercise of large muscle groups is emphasized.
2.      There are four methods of training that challenge the aerobic system: continuous, interval (work relief), circuit,and circuit interval.

Continuous Training
1.      A submaximum energy requirement, sustained through out the training period, is imposed.
2.      Once the steady state is achieved, the muscle obtains energy by means of aerobic metabolism. Stress is placed primarily on the slow-twitch fiber
3.      The activity can be prolonged for 20 to 60 minutes without exhausting the oxygen transport system.
4.      The work rate is increased progressively as training improvements are achieved. Overload can be accomplished by increasing the exercise duration.
5.      In the healthy individual, continuous training is the most effective way to improve endurance.
Interval Training
  Interval training tends to improve strength and power more than endurance.
1.      The relief interval is either a rest relief (passive recovery) or a work relief (active recovery); and its duration ranges from a few seconds to several minutes. Work recovery involves continuing the exercise but at a reduced level from the work period. During the relief period, a portion of the muscular stores of ATP and the oxygen associated with myoglobin that were depleted during the work period are replenished by the aerobic system; an increase in .VO2 max occurs.
2.      The longer the work interval, the more the aerobic system is stressed. With a short work interval, the duration of the rest interval is critical if the aerobic system is to be stressed (a work/recovery ratio of 1:1 to 1:5 is appropriate). A rest interval equal to one and a half times the work interval allows the succeeding exercise interval to begin before recovery is complete and stresses the aerobic system. With a longer work interval, the duration of the rest is not as important.
3.      A significant amount of high-intensity work can be achieved with interval or intermittent work if there is appropriate spacing of the work–relief intervals. Thetotal amount of work that can be completed with intermittent work is greater than the amount of work that can be completed with continuous training.
Circuit Training
Circuit training employs a series of exercise activities. At the end of the last activity, the individual starts from the beginning and again moves through the series. The series of activities is repeated several times.
1.      Several exercise modes can be used involving large andsmall muscle groups and a mix of static or dynamic effort.
2.      Use of circuit training can improve strength and endurance by stressing both the aerobic and anaerobic systems.
Circuit-Interval Training
1.      Combining circuit and interval training is effective because of the interaction of aerobic and anaerobic production of ATP.
2.      In addition to the aerobic and anaerobic systems being stressed by the various activities, with the relief interval there is a delay in the need for glycolysis and the production of lactic acid prior to the availability of oxygen supplying the ATP.
Cool-Down Period:
A cool-down period is necessary following the exercise period.
Purpose:
1.      Prevent pooling of the blood in the extremities by continuing to use the muscles to maintain venous return.
2.      Prevent fainting by increasing the return of blood to the heart and brain as cardiac output and venous return decreases.
3.      Enhance the recovery period with the oxidation of metabolic waste and replacement of the energy stores.
4.      Prevent myocardial ischemia, arrhythmias, or other cardiovascular complications.
Guidelines:
        Total-body exercises such as calisthenics and static stretching are appropriate.
The period should last 5 to 10 minutes.(22)

5. STRESS MANAGEMENT :
Belly breathing
1.      Sit or lie flat in a comfortable position.
2.      Put one hand on your belly just below your ribs and the other hand on your chest.
3.      Take a deep breath in through your nose, and let your belly push your hand out. Your chest should not move.
4.      Breathe out through pursed lips as if you were whistling. Feel the hand on your belly go in, and use it to push all the air out.
5.      Do this breathing 3 to 10 times. Take your time with each breath.
6.      Notice how you feel at the end of the exercise.
4-7-8 breathing
1.      To start, put one hand on your belly and the other on your chest as in the belly breathing exercise.
2.      Take a deep, slow breath from your belly, and silently count to 4 as you breathe in.
3.      Hold your breath, and silently count from 1 to 7.
4.      Breathe out completely as you silently count from 1 to 8. Try to get all the air out of your lungs by the time you count to 8.
5.      Repeat 3 to 7 times or until you feel calm.
6.      Notice how you feel at the end of the exercise.
Roll breathing
  Roll breathing helps you to develop full use of your lungs and to focus on the rhythm of your breathing.
1.      Put your left hand on your belly and your right hand on your chest. Notice how your hands move as you breathe in and out.
2.      Practice filling your lower lungs by breathing so that your "belly" (left) hand goes up when you inhale and your "chest" (right) hand remains still. Always breathe in through your nose and breathe out through your mouth. Do this 8 to 10 times.
3.      When you have filled and emptied your lower lungs 8 to 10 times, add the second step to your breathing: inhale first into your lower lungs as before, and then continue inhaling into your upper chest. Breathe slowly and regularly. As you do so, your right hand will rise and your left hand will fall a little as your belly falls.
4.      As you exhale slowly through your mouth, make a quiet, whooshing sound as first your left hand and then your right hand fall. As you exhale, feel the tension leaving your body as you become more and more relaxed.
5.      Practice breathing in and out in this way for 3 to 5 minutes. Notice that the movement of your belly and chest rises and falls like the motion of rolling waves.
6.      Notice how you feel at the end of the exercise.
MORNING BREATHING
1.      From a standing position, bend forward from the waist with your knees slightly bent, letting your arms dangle close to the floor.
2.      As you inhale slowly and deeply, return to a standing position by rolling up slowing, lifting your head last.
3.      Hold your breath for just a few seconds in this standing position.
4.      Exhale slowly as you return to the original position, bending forward from the waist.
5.      Notice how you feel at the end of the exercise(23)

6.  PSYCHOLOGICAL  ADAPTATION:
1.      Autogenic Training
2.      Biofeedback-Assisted Relaxation
3.      Deep Breathing or Breathing Exercises
4.      Guided Imagery
5.      Progressive Muscular  Relaxation
6.      Coping strategies

7. SELF MANAGEMENT:
1.      Occupation Based Self Management intervention
2.      Motivational Interviewing to promote lifestyle change
3.      Culturally Tailored Healthy Lifestyle training
4.      Evidence informed, theory-driven practice
5.      Interventions to address health disparities
6.      Client driven action planning and goal setting
7.      Environmental modification to promote engagement in meaningful occupations
8.      Translation of health recommendations to the client’s everyday life(24)

8. ENERGY CONSERVATION PRINCIPLES AND TECHNIQUES:
Organization:
1.      Planning ahead
2.      Prioritize your work
3.      Analyze the work to be done
4.      Eliminate all unnecessary steps
5.      Combine tasks or activities
6.       Consider making changes to tasks or activity

Balance Rest and Activity:
1.      Frequent short rests are of more benefit than fewer longer ones
2.      The amount of rest you need and the amount of activity you can do will vary day to day
3.      Plan your work so difficult tasks are done during your best time of day and are distributed throughout the week
4.      Avoid activities which cannot be stopped immediately if they become too stressful
5.      Rest before you tire
6.      Plan a balance of work, recreation, exercise, and rest
7.      If possible, lie down to rest
8.      Practice breathing techniques

9.WORK SIMPLIFICATION TECHNIQUES:
1.      Cancel tasks that are not really necessary
2.      Delegate responsibilities to others
3.      Simplify your methods of work
4.      Sit to work whenever possible
5.      Adjust height of work surfaces to allow for good posture
6.      Use equipment when necessary to conserve energy
7.      Avoid prolong exposure to moist heat(25)

10.JOINT PROTECTION PRINCIPLES:
1.      Respect For Pain
2.      Balance Activity And Rest
3.       Avoid Activities Which Cannot Be Stopped
4.       Use Larger, Stronger Joints For Activities, When Possible, Distributing The Weight  Over Non-involved Or Stronger Joints.
5.      Avoid Staying In One Position For Extended Periods Of Time.
6.      Maintain Or Use Your Joints In Good Alignment.(26)

11.SELF HELP, ENVIRONMENT AND HOME: (ADAPTATION AND MODIFICATION )
INFECTION CONTROL:
1.      Handwashing
2.       Covering your cough
3.      Appropriate gloving
4.       Cleaning, sanitizing, and disinfection
5.       Food safety
6.       Exclusion guidelines Avoid sharing personal items
7.       Promote self-care
HOME  AND ENVIRONMENT (ADAPTATION  AND MODIFICATION)
1.      Consider the safety of family
2.      Follow the label instructions for mixing, using, and storing solutions.
3.       Store these products safely out of reach of family
4.      Clean soiled surfaces and items before using sanitizers or disinfectants.Use warm/hot water with any household soap or detergent
5.      Change water when it looks or feels dirty, after cleaning bathrooms and diaper changing area, and after cleaning the kitchen
6.      Always clean the least dirty items and surfaces first (for example, countertops before floors, sinks before toilets)
7.      Always clean high surfaces first, then low surfaces
8.      Disposable towels are preferred for cleaning. If using reusable cloths/rags, launder between cleaning uses. DO NOT use sponges since they are hard to clean
9.       Clean completely on a regular schedule and spot clean as needed
10.  Items washed /sanitizers/air dired immediately after each uses






















REFERENCES:
1.      WHO (2003), Weekly Epidemiological Record No. 12, 21March2003.
2.      WHO (2003), World Health Report 2003, Shaping the future.
3.      WHO (2003), Weekly Epidemiological Record No. 43, 24th Oct. 2003.
4.      WHO (2009), Weekly Epidemiological Record No. 7, 13th Feb. 2009.
5.      Stephen J. Mcphee et al, (2010), Current Medical Diagnosis and Treatment, 49th Ed. A Lange Medical Publication.
7.      .https://www.ersnet.org/the-society/news/novel-coronavirus-outbreak--update-and-information-for-healthcare-professionals
8.      Green E, Walters ED, Green AM, et al: Feedback technique fordeep relaxation, Psychophysiology 6(3):371–377, 1969.
9.      Breslin EH: The pattern of respiratory muscle recruitment during pursed-lip breathing, Chest 101(1):75–78, 1992.
10.  Migliore A: Management of dyspnea guidelines for practice for adults with chronic obstructive pulmonary disease, Occupational Therapy Health Care 18(3), 2004.
11.   Green E: Biofeedback techniques for deep relaxation, Psychophysiology 6(3):371, 1969.
12.  Hodgkin JE, Celli BR, Connors GL: Pulmonary rehabilitation guidelines to success, ed 3, Philadelphia, Pa, 2000, Lippincott Williams & Wilkins.
13.  Maloney FP, Moss K: Energy requirements for selected activities, Denver, Colo, 1974, Department of Physical Medicine, National Jewish Hospital
14.   Occupational Therapy Practice Of Frame Work :Domain & Process 3rd Edition
15.  WHO (1981). Techn.Rep.Ser., No.668.
16.    WHO (1969). Techn.Rep.Ser., No.419.
20.   occupational therapy review  guide   rev 2.11.2018
21.    Hillegass, S, Sadowsky, H: Essentials of Cardiopulmonary Physical Therapy, ed 2. WB Saunders, Philadelphia, 2001

22.   Irwin, S, Teckline, JS: Cardiopulmonary Physical Therapy, ed 4. CV Mosby, St. Louis, 2004.
26.  Cordery, Joy Cumberland, M.A.O.T., OTR, “Joint Protection - A Responsibility for the  Occupational Therapist,” American Journal of Occupational Therapy, XIX, %, 1965.
27.  Prevention and Control of Communicable DiseasesEditors: Barbara Wolkoff Autumn Grim Harvey L. Marx, Jr.


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